Berberine is a bright yellow alkaloid extracted from plants such as Indian Barberry (tree turmeric), Oregon Grape and goldenseal.

Plants containing Berberine have been used in traditional Ayurvedic and Chinese medicine as an antibacterial, anti-inflammatory, anti-diarrheal, anti-microbial, anti-protozoal and immune-enhancing therapy for thousands of years.

Berberine is one of the very few nootropic supplements known to activate AMPK (another is Resveratrol).

Activating AMPK is especially relevant if you’re diabetic, pre-diabetic, or over-weight. All conditions that negatively affect cognition. Research and clinical experience has shown Berberine to be as effective in controlling diabetes as the prescription drug metformin.

Berberine is one of the most powerful (literally) nootropic supplements on our List of Nootropics. Not only can Berberine help control diabetes, but you may find sugar cravings disappear. No crashes late afternoon. Energy levels and stamina increase.

Adding Berberine to your nootropic stack can help improve cholesterol levels, lower blood pressure, improve your mood, protect your brain from damage, and help memory.

Dosing Berberine as a nootropic is 500 mg 3-times per day. If you are dealing with a medical condition, or are taking any medication (including antibiotics), you should speak with your doctor before taking Berberine. Especially if you’re currently using blood-sugar lowering medication.

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